UK - Future outbreaks of foot-and-mouth disease (FMD) can be controlled effectively and quickly with vaccinations - saving millions of pounds and hundreds of thousands of livestock - according to research by the University of Warwick.Dr Michael Tildesley and Naomi Bradbury from the School of Life Sciences have discovered that a key issue for successfully containing and eradicating a FMD outbreak is to establish how many animals can be vaccinated per day, and tailor controls accordingly.Using a mathematical model of the UK farming landscape, Dr Tildesley and colleagues simulated numerous scenarios of infection - to varying levels of severity and speed - calculating the most effective and efficient approaches to stave the spread of disease.Many dangerous uncertainties exist when dealing with epidemics like FMD, such as: the efficacy of vaccinations, the time it takes for livestock to become immune after receiving vaccines, and the number of vaccine doses available. Uncertainty leads to huge potential losses of both money and livestock.

根據(jù)英國(guó)華威大學(xué)的研究顯示，未來(lái)的口蹄疫疫情可以通過(guò)疫苗接種而被迅速和有效的控制，從而節(jié)省上百萬(wàn)英鎊，挽救成百上千的牲畜。生命科學(xué)學(xué)院的娜奧米·布拉德伯里與邁克爾·蒂爾茲利博士已經(jīng)發(fā)現(xiàn)了一個(gè)可以成功遏制和根除口蹄疫疫情的關(guān)鍵問(wèn)題，即建立一套統(tǒng)計(jì)每天接種疫苗動(dòng)物數(shù)量的機(jī)制，并相應(yīng)的對(duì)疫苗接種做出調(diào)整控制。蒂爾茲利博士和他的同事通過(guò)使用英國(guó)農(nóng)業(yè)景觀的數(shù)學(xué)模型，按照不同的疫情嚴(yán)重程度和感染速度，對(duì)許多感染狀況進(jìn)行了仿真，計(jì)算出了避免疾病傳播的最有效和最高效的方法。在處理像口蹄疫這樣的傳染病時(shí)，存在著許多危險(xiǎn)的不確定性，比如：疫苗藥效、牲畜在接種疫苗后對(duì)疾病免疫的耗費(fèi)時(shí)間，可用的疫苗藥劑數(shù)量。不確定性會(huì)導(dǎo)致金錢(qián)和牲畜受到巨額的潛在損失。